Cancer

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26 Mar 2024
28

Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system.[2] Symptoms may include a lump in the testicle or swelling or pain in the scrotum.[2] Treatment may result in infertility.[2]

Testicular cancer
Other names
Testis tumor[1]

7.4 × 5.5-cm seminoma in a radical orchiectomy specimen.
Specialty
Oncology
Symptoms
Lump in the testicle, swelling or pain in the scrotum[2]
Usual onset
20 to 34 years old males[3]
Types
Germ cell tumors (seminomas and nonseminomas), sex-cord stromal tumors, lymphomas[4][5]
Risk factors
Undescended testis, family history of the disease, previous history of testicular cancer[5]
Diagnostic method
Physical exam, ultrasound, blood tests, surgical removal of the testicle[2]
Differential diagnosis
Spermatocele, epididymitis, inguinal hernia, appendix testis[1]
Treatment
Surgery, radiation therapy, chemotherapy, stem cell transplantation[2]
Prognosis
Five-year survival rate rates ~ 95% (US)[3]
Frequency
686,000 (2015)[6]
Deaths
9,400 (2015)[7]
Risk factors include an undescended testis, family history of the disease, and previous history of testicular cancer.[5] More than 95% are germ cell tumors which are divided into seminomas and non-seminomas.[8] Other types include sex-cord stromal tumors and lymphomas.[4] Diagnosis is typically based on a physical exam, ultrasound, and blood tests.[2] Surgical removal of the testicle with examination under a microscope is then done to determine the type.[2]

Testicular cancer is highly treatable and usually curable.[5] Treatment options may include surgery, radiation therapy, chemotherapy, or stem cell transplantation.[2] Even in cases in which cancer has spread widely, chemotherapy offers a cure rate greater than 80%.[4]

Globally testicular cancer affected about 686,000 people in 2015.[6] That year it resulted in 9,400 deaths up from 7,000 deaths in 1990.[7][9] Rates are lower in the developing than the developed world.[10] Onset most commonly occurs in males 20 to 34 years old, rarely before 15 years old.[3][11] The five-year survival rate in the United States is about 95%.[3] Outcomes are better when the disease remains localized.[3]Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system.[2] Symptoms may include a lump in the testicle or swelling or pain in the scrotum.[2] Treatment may result in infertility.[2]
Testicular cancer
Other names
Testis tumor[1]
7.4 × 5.5-cm seminoma in a radical orchiectomy specimen.
Specialty
Oncology
Symptoms
Lump in the testicle, swelling or pain in the scrotum[2]
Usual onset
20 to 34 years old males[3]
Types
Germ cell tumors (seminomas and nonseminomas), sex-cord stromal tumorslymphomas[4][5]
Risk factors
Undescended testis, family history of the disease, previous history of testicular cancer[5]
Diagnostic method
Physical examultrasoundblood testssurgical removal of the testicle[2]
Differential diagnosis
Spermatoceleepididymitisinguinal herniaappendix testis[1]
Treatment
Surgery, radiation therapychemotherapystem cell transplantation[2]
Prognosis
Five-year survival rate rates ~ 95% (US)[3]
Frequency
686,000 (2015)[6]
Deaths
9,400 (2015)[7]
Risk factors include an undescended testis, family history of the disease, and previous history of testicular cancer.[5] More than 95% are germ cell tumors which are divided into seminomas and non-seminomas.[8] Other types include sex-cord stromal tumors and lymphomas.[4] Diagnosis is typically based on a physical examultrasound, and blood tests.[2] Surgical removal of the testicle with examination under a microscope is then done to determine the type.[2]
Testicular cancer is highly treatable and usually curable.[5] Treatment options may include surgery, radiation therapychemotherapy, or stem cell transplantation.[2] Even in cases in which cancer has spread widely, chemotherapy offers a cure rate greater than 80%.[4]
Globally testicular cancer affected about 686,000 people in 2015.[6] That year it resulted in 9,400 deaths up from 7,000 deaths in 1990.[7][9] Rates are lower in the developing than the developed world.[10] Onset most commonly occurs in males 20 to 34 years old, rarely before 15 years old.[3][11] The five-year survival rate in the United States is about 95%.[3] Outcomes are better when the disease remains localized.[3]Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system.[2] Symptoms may include a lump in the testicle or swelling or pain in the scrotum.[2] Treatment may result in infertility.[2]
Testicular cancer
Other names
Testis tumor[1]
7.4 × 5.5-cm seminoma in a radical orchiectomy specimen.
Specialty
Oncology
Symptoms
Lump in the testicle, swelling or pain in the scrotum[2]
Usual onset
20 to 34 years old males[3]
Types
Germ cell tumors (seminomas and nonseminomas), sex-cord stromal tumorslymphomas[4][5]
Risk factors
Undescended testis, family history of the disease, previous history of testicular cancer[5]
Diagnostic method
Physical examultrasoundblood testssurgical removal of the testicle[2]
Differential diagnosis
Spermatoceleepididymitisinguinal herniaappendix testis[1]
Treatment
Surgery, radiation therapychemotherapystem cell transplantation[2]
Prognosis
Five-year survival rate rates ~ 95% (US)[3]
Frequency
686,000 (2015)[6]
Deaths
9,400 (2015)[7]
Risk factors include an undescended testis, family history of the disease, and previous history of testicular cancer.[5] More than 95% are germ cell tumors which are divided into seminomas and non-seminomas.[8] Other types include sex-cord stromal tumors and lymphomas.[4] Diagnosis is typically based on a physical examultrasound, and blood tests.[2] Surgical removal of the testicle with examination under a microscope is then done to determine the type.[2]
Testicular cancer is highly treatable and usually curable.[5] Treatment options may include surgery, radiation therapychemotherapy, or stem cell transplantation.[2] Even in cases in which cancer has spread widely, chemotherapy offers a cure rate greater than 80%.[4]
Globally testicular cancer affected about 686,000 people in 2015.[6] That year it resulted in 9,400 deaths up from 7,000 deaths in 1990.[7][9] Rates are lower in the developing than the developed world.[10] Onset most commonly occurs in males 20 to 34 years old, rarely before 15 years old.[3][11] The five-year survival rate in the United States is about 95%.[3] Outcomes are better when the disease remains localized.[3]

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